GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs3772130 | 1 | rs13083794 | chr3:121464928 | IQCB1 | chr3:121488610-121553926:- | 0.45 | 4.25 | 5.03E-5 | Cognitive performance |
| THYM | cis | rs3772130 | 1 | rs13087578 | chr3:121369207 | IQCB1 | chr3:121488610-121553926:- | 0.48 | 4.39 | 2.98E-5 | Cognitive performance |
| THYM | cis | rs9815354 | 1 | rs13087719 | chr3:41951576 | ULK4 | chr3:41288091-42003660:- | -1.02 | -11.47 | 1.23E-19 | Diastolic blood pressure |
| THYM | cis | rs10935120 | 1 | rs13087875 | chr3:134261123 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs13087875 | chr3:134261123 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
| THYM | cis | rs9847710 | 1 | rs13088455 | chr3:53087482 | ITIH4 | chr3:52847007-52866554:- | 0.27 | 4.18 | 6.51E-5 | Ulcerative colitis |
| THYM | cis | rs10935120 | 1 | rs13089966 | chr3:134279197 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs13089966 | chr3:134279197 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
| THYM | cis | rs10935120 | 1 | rs13090969 | chr3:134307257 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.1 | 1.9E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs13090969 | chr3:134307257 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.93 | 4.96E-8 | Height |
| THYM | cis | rs9876781 | 1 | rs13091785 | chr3:48494098 | TREX1 | chr3:48501186-48509043:+ | -0.28 | -4.22 | 5.51E-5 | Longevity |
| THYM | cis | rs10935120 | 1 | rs13096604 | chr3:134250099 | ANAPC13 | chr3:134196547-134204865:- | -0.59 | -8.13 | 1.58E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs13096604 | chr3:134250099 | CEP63 | chr3:134204575-134293852:+ | -0.41 | -5.87 | 6.33E-8 | Height |
| THYM | cis | rs13168670 | 1 | rs13168670 | chr5:140146899 | WDR55 | chr5:140044384-140050551:+ | -0.35 | -4.23 | 5.34E-5 | Schizophrenia |
| THYM | cis | rs1577917 | 1 | rs13194429 | chr6:86646705 | SNHG5 | chr6:86386726-86388451:- | -0.57 | -6.89 | 5.95E-10 | Response to antipsychotic treatment |